Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin.
Raymond Joseph Deshaies (born September 25, 1961) is an American biochemist and cell biologist. He is Senior Vice President of global research at Amgen and a Visiting Associate at the California Institute of Technology (Caltech). Prior to that, he was a Professor of Biology at Caltech and an Investigator of the Howard Hughes Medical Institute.He is also the co-founder of the biotechnology.
The myeloid leukemia-associated protein SET is a potent inhibitor of protein phosphatase 2A. Li M, Makkinje A, Damuni Z. J Biol Chem. 1996 May 10;271(19):11059-62. PMID 8626647: SET protein (TAF1beta, I2PP2A) is involved in neuronal apoptosis induced by an amyloid precursor protein cytoplasmic subdomain. Madeira A, Pommet JM, Prochiantz A.
ATXN3 interacts with the mammalian p97 protein, a chaperone-like AAA ATPase, to regulate the degradation of misfolded ER proteins (Wang et al., 2006). In C. elegans the p97 homologue is CDC-48. Worms deficient for both cdc-82 and atx-3 have increased protein stability and increased longevity (Kuhlbrodt et al., 2011). Thus, it seems that ATX-3.
What plant proteins can tell us about Alzheimer’s. Plant biologists have described how a protein called CC1 helps plants to grow under salt stress and, intriguingly, it shares features with a protein linked to Alzheimer’s disease. By Dr Daryl Holland, University of Melbourne. Share selection to: Alzheimer’s disease and other forms of dementia are a growing burden on society and a.
Pierce Protein Assays provide a wide range of options for accurate protein concentration determination based on assay time, sensitivity, compatibility, standard curve linearity, and protein-to-protein variation. Although this article uses Pierce Protein Assay products as examples, the principles and chemistries discussed apply generally to most available colorimetric or fluorometric protein.
Civil Rights Argumentative Essay About Same Sex Marriage. This Argumentative essay will discuss the argument of same sex marriage. The contents are: meaning, brief background and thesis statement for the Introduction; for the Body of the discussion is the counter argument; and for the conclusion part: the summary and the restatement of the thesis statement.
Li et al. determine the crystal structure of human Spartan bound to DNA. Spartan is a DNA-activated metalloprotease that cleaves DNA-protein crosslinks to preserve genome stability. Spartan mutations cause progeria and liver cancer in humans. The structure provides important insights into how DNA activates the protease activity of Spartan.